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Tratamiento de la amiloidosis cardíaca por transtiretina

Federico Weckesser, Juan P Costabel

Revista del Consejo Argentino de Residentes de Cardiología ;():0161-0167 


La amiloidosis representa un conjunto de enfermedades ocasionadas por el depósito de un grupo de proteínas denominadas “amiloide”.
El compromiso cardíaco es la principal causa de morbimortalidad en la amiloidosis sistémica, independientemente de la patogenia productora del amiloide subyacente.
Solo dos tipos de amiloidosis son las responsables de más del 95% de las amiloidosis cardíacas: la amiloidosis por cadenas livianas y la amiloidosis por transtiretina (ATTR).
En el siguiente trabajo nos propusimos resumir los conceptos más importantes en relación al manejo de los pacientes con ATTR.


Palabras clave: amiloidosis, tratamiento, amiloidosis de cadenas livianas,

Amyloidosis represents a group of diseases caused by the deposit of a group of proteins called “amyloid”.
Cardiac involvement is the main cause of morbidity and mortality in systemic amyloidosis, regardless of the underlying amyloid-producing pathogenesis.
Only two types of amyloidosis are responsible for more than 95% of cardiac amyloidosis: light chain amyloidosis and transthyretin amyloidosis (ATTR).
In the following study, we set out to summarize the most important concepts in relation to the management of patients with ATTR.


Keywords: amyloidosis, treatment, immunoglobulin light-chain amyloidosis,


Los autores declaran no poseer conflictos de intereses.

Fuente de información Consejo Argentino de Residentes de Cardiología. Para solicitudes de reimpresión a Revista del CONAREC hacer click aquí.

Recibido 2020-06-12 | Aceptado 2020-07-19 | Publicado 2020-08-31

Figura 1. Opciones de tratamiento.

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Autores

Federico Weckesser
Residente Servicio de Cardiología.
Juan P Costabel
Jefe de Unidad Coronaria. Servicio de Cardiología Clínica y Crítica del Instituto Cardiovascular de Buenos Aires.

Autor correspondencia

Federico Weckesser
Residente Servicio de Cardiología.

Correo electrónico: fweckesser@icba.com.ar

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Titulo
Tratamiento de la amiloidosis cardíaca por transtiretina

Autores
Federico Weckesser, Juan P Costabel

Publicación
Revista del CONAREC

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Consejo Argentino de Residentes de Cardiología

Fecha de publicación
2020-08-31

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© Consejo Argentino de Residentes de Cardiología

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